丝状支原体丝状亚种

丝状支原体丝状亚种Mycoplasma mycoides subsp. mycoides,缩写Mmm)是支原体科支原体属丝状支原体的一个细菌亚种。它是引起牛传染性胸膜肺炎的致病菌[1]

丝状支原体丝状亚种
科学分类 编辑
域: 细菌域 Bacteria
门: 厚壁菌门 Bacillota
纲: 柔膜菌纲 Mollicutes
目: 支原体目 Mycoplasmatales
科: 支原体科 Mycoplasmataceae
属: 支原体属 Mycoplasma
种:
丝状支原体 M. mycoides
亚种:
丝状支原体丝状亚种 M. m. subsp. mycoides
三名法
Mycoplasma mycoides subsp. mycoides

形态特征

丝状支原体丝状亚种没有细胞壁,菌体外层由荚膜黏附结构黏附相关蛋白组成,内层为三层结构的细胞膜,能在不同形态之间迅速转换[2]。菌体直径为125~250纳米,可呈现丝状、环状、分枝状等多种形态,最常见的是球状[1]

丝状支原体丝状亚种在革兰氏染色中呈阴性[1],其基因组双链环状DNA[3]

敏感性和耐药性

丝状支原体丝状亚种对一些常见的消毒剂以及紫外线、加热、酸碱环境等较为敏感;一些抗菌药物,如大环内酯四环素氟喹诺酮抗生素可以抑制其生长;对青霉素醋酸铊磺胺类抗生素等药物具有很高的耐药性[4]

参考文献

  1. ^ 1.0 1.1 1.2 Xin, JiuQing; Pan, Qiao; Li, Yuan. The eradication of contagious bovine pleuropneumonia in China. SCIENTIA SINICA Vitae. 2023-12-01. doi:10.1360/SSV-2023-0162. 
  2. ^ Nicholas, R.A.J.; Bashiruddin, J.B. Mycoplasma mycoides subspecies mycoides (Small colony variant): the agent of contagious bovine pleuropneumonia and member of the “Mycoplasma mycoides cluster”. Journal of Comparative Pathology. 1995-07, 113 (1): 1–27. doi:10.1016/S0021-9975(05)80065-9. 
  3. ^ Westberg, Joakim; Persson, Anja; Holmberg, Anders; Goesmann, Alexander; Lundeberg, Joakim; Johansson, Karl-Erik; Pettersson, Bertil; Uhlén, Mathias. The Genome Sequence of Mycoplasma mycoides subsp. mycoides SC Type Strain PG1 T , the Causative Agent of Contagious Bovine Pleuropneumonia (CBPP). Genome Research. 2004-02, 14 (2): 221–227. doi:10.1101/gr.1673304. 
  4. ^ Mitchell, John D.; Goh, Shan; McKellar, Quintin A.; McKeever, Declan J. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. The Veterinary Journal. 2013-09, 197 (3): 806–811. doi:10.1016/j.tvjl.2013.05.025.