扁平苔藓
扁平苔藓(Lichen planus)是一种表皮慢性病,屬於丘疹鱗屑性疾患的一種,常见于皮肤、口腔、舌头。病徵包含但不限于:丘疹[1],溃烂,瘙痒,红疹,白色斑片。可以在显微镜下观察切片而确诊。
扁平苔藓 Lichen planus | |
---|---|
扁平苔藓患者的皮膚 | |
类型 | lichen disease[*]、疾病 |
分类和外部资源 | |
醫學專科 | 皮肤病学 |
ICD-11 | EA91 |
ICD-10 | L43 |
ICD-9-CM | 697.0 |
DiseasesDB | 7452 |
MedlinePlus | 000867 |
eMedicine | derm/233 derm/663 |
MeSH | D008010 |
Orphanet | 254367 |
本病與苔藓完全無關,會令皮膚出現一種好像長在樹幹上的苔藓樣的乾燥波紋,因而得名。現時已知道病因可能與氧化壓力(oxidative stress)相關[2][3],也與某些藥物及疾病有關聯,但在背後的病理機制及具體的发病原因尚不明确。
治療
扁平苔藓現時未有特效的辦法治療。为舒緩病況,可使用消炎的口服藥物或外敷药物,如糖皮质激素类药物地奈德。另外現時有其他研究使用以下方式治療:
參考資料
- ^ 道兰氏医学词典中的lichen planus
- ^ Ioana Scrobotă, Teodora Mocan, C. Cătoi, P. Bolfă, Adriana Mureşan, G. Băciuţ. Histopathological aspects and local implications of oxidative stress in patients with oral lichen planus. Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie. 2011, 52 (4): 1305–1309 [2019-02-13]. ISSN 1220-0522. PMID 22203938. (原始内容存档于2019-08-13).
- ^ D. G. Aly, R. S. Shahin. Oxidative stress in lichen planus. Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica. 2010, 19 (1): 3–11 [2019-02-13]. ISSN 1581-2979. PMID 20372767. (原始内容存档于2019-08-19).
- ^ Pavlotsky F, Nathansohn N, Kriger G, Shpiro D, Trau H. Ultraviolet-B treatment for cutaneous lichen planus: our experience with 50 patients. Photodermatol Photoimmunol Photomed. April 2008, 24 (2): 83–6. PMID 18353088. doi:10.1111/j.1600-0781.2008.00344.x.
- ^ Choonhakarn C, Busaracome P, Sripanidkulchai B, Sarakarn P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br. J. Dermatol. March 2008, 158 (3): 573–7. PMID 18093246. doi:10.1111/j.1365-2133.2007.08370.x.[永久失效連結]
- ^ Agha-Hosseini F, Borhan-Mojabi K, Monsef-Esfahani HR, Mirzaii-Dizgah I, Etemad-Moghadam S, Karagah A. Efficacy of purslane in the treatment of oral lichen planus. Phytother Res. Feb 2010, 24 (2): 240–4. PMID 19585472. doi:10.1002/ptr.2919.