醋酸左炔诺孕酮
化合物
醋酸左炔诺孕酮(英語:Levonorgestrel acetate,缩写LNG-A,化学名:左炔诺孕酮-17β-乙酸酯,levonorgestrel 17β-acetate),是一种有机化合物,分子式为C23H30O3,属于19-去甲孕酮型孕激素,从未上市销售[1][2][3][4]。
臨床資料 | |
---|---|
其他名稱 | LNG-A; LNGA; 3-Ketonorgestimate; Levonorgestrel 17β-acetate; D-(–)-Norgestrel 17β-acetate; 17α-Ethynyl-18-methylestr-4-en-17β-ol-3-one 17β-acetate; 17β-Acetoxy-13β-ethyl-17α-ethynylgon-4-en-3-one |
藥物類別 | 孕激素 |
识别信息 | |
| |
CAS号 | 13732-69-9( 18290-31-8) |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.123.252 |
化学信息 | |
化学式 | C23H30O3 |
摩尔质量 | 354.49 g·mol−1 |
3D模型(JSmol) | |
| |
|
参考文献
- ^ Naderi S, Fotherby K. Long-acting contraceptive agents: in vitro hydrolysis of esters of norethisterone and levonorgestrel. Steroids. 1983, 41 (3): 397–417. PMID 6419410. S2CID 28094296. doi:10.1016/0039-128x(83)90110-1.
- ^ Kuhl H. Pharmacology of estrogens and progestogens: influence of different routes of administration (PDF). Climacteric. 2005, 8 (Suppl 1): 3–63. PMID 16112947. S2CID 24616324. doi:10.1080/13697130500148875.
- ^ Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH. Classification and pharmacology of progestins. Maturitas. 2008, 61 (1–2): 171–80. PMID 19434889. doi:10.1016/j.maturitas.2008.11.013.
- ^ Alvarez-Sanchez F, Brache V, Jackanicz T, Faundes A. Evaluation of four different contraceptive vaginal rings: steroid serum levels, luteal activity, bleeding control and lipid profiles. Contraception. 1992, 46 (4): 387–98. PMID 1486777. doi:10.1016/0010-7824(92)90101-x.