11-脱氢皮质酮

11-脱氢皮质酮
	IUPAC名; 21-Hydroxypregn-4-ene-3,11,20-trione
	系统名; (1S,3aS,3bS,9aR,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,8,9,9a,9b,11,11a-dodecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione
别名	11-DHC; 11-Oxocorticosterone; 17-Deoxycortisone
识别
CAS号	72-23-1
PubChem	5311364
ChemSpider	4470861
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C;
ChEBI	78600
性质
化学式	C21H28O4
摩尔质量	344.44 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

11-脱氢皮质酮（英語：11-Dehydrocorticosterone，缩写11-DHC，或称为17-脱氧可的松，17-deoxycortisone，21-羟基孕-4-烯-3,11,20-三酮，21-hydroxypregn-4-ene-3,11,20-trione）是一种有机化合物，化学式为C₂₁H₂₈O₄，是一种内源性的盐皮质激素^[1]。

参考文献

^ Harno, E; Cottrell, EC; Keevil, BG; DeSchoolmeester, J; Bohlooly-Y, M; Andersén, H; Turnbull, AV; Leighton, B; White, A. 11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.. Endocrinology. 2013-10, 154 (10): 3599–609. PMID 23832962. doi:10.1210/en.2013-1362.

外部链接

[1] Harno, E; Cottrell, EC; Keevil, BG; DeSchoolmeester, J; Bohlooly-Y, M; Andersén, H; Turnbull, AV; Leighton, B; White, A. 11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.. Endocrinology. 2013-10, 154 (10): 3599–609. PMID 23832962. doi:10.1210/en.2013-1362.

[1]

11-脱氢皮质酮

IUPAC名 21-Hydroxypregn-4-ene-3,11,20-trione
系统名 (1S,3aS,3bS,9aR,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,8,9,9a,9b,11,11a-dodecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione
别名	11-DHC; 11-Oxocorticosterone; 17-Deoxycortisone
识别
CAS号	72-23-1
PubChem	5311364
ChemSpider	4470861
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C
ChEBI	78600
性质
化学式	C₂₁H₂₈O₄
摩尔质量	344.44 g·mol⁻¹
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。