2,4,5-三羟基甲基苯丙胺

化合物

2,4,5-三羟基甲基苯丙胺(英語:2,4,5-Trihydroxymethamphetamine,缩写THMA)是一种神經毒素,分子式C10H15NO3,也是MDMA(3,4-亚甲二氧甲基苯丙胺)在体内的代谢产物[1][2]

2,4,5-三羟基甲基苯丙胺
IUPAC名
5-[2-(Methylamino)propyl]benzene-1,2,4-triol
识别
CAS号 136706-32-6
PubChem 131985
ChemSpider 19983112
SMILES
 
  • CNC(C)CC1=C(O)C=C(O)C(O)=C1
性质
化学式 C10H15NO3
摩尔质量 197.23 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

另见

参考文献

  1. ^ Ikram Elayan; James W. Gibb; Glen R. Hanson; Rodger L. Foltza; Heng Keang Lima; Michel Johnson. Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine but not by 2-hydroxy-4,5-methylenedioxymethamphetamine or2-hydroxy-4,5-methylenedioxyamphetamine. European Journal of Pharmacology. 1992, 221 (2–3): 281–288. PMID 1358654. doi:10.1016/0014-2999(92)90714-F. 
  2. ^ Anne Neudörffer; Melanie Mueller; Claire-Marie Martinez; Annis Mechan; Una McCann; George A. Ricaurte; Martine Largeron. Synthesis and Neurotoxicity Profile of 2,4,5-Trihydroxymethamphetamine and its 6-(N-Acetylcystein-S-yl) Conjugate. Chem Res Toxicol. 2011, 24 (6): 968–978. PMC 3124246 . PMID 21557581. doi:10.1021/tx2001459. 

外部链接