ERV-Fc是一类內源性反轉錄病毒家族[1],广泛存在于真兽类基因组[2],由3000万年至1500万年间不断感染真兽类的γ-逆转录病毒整合而来,此病毒与现在的小鼠白血病病毒英语Murine leukemia virus猫白血病病毒(FeLV)关系最接近[3]灵长类特别是人类基因组中有两段ERV-Fc[4],分别是位于X染色体的HERV-Fc1和位于7号染色体的HERV-Fc2,代表了两次γ-逆转录病毒整合事件[5]

各種內源性反轉錄病毒的分類關係,ERV-Fc属于Class I,与ERV-H关系最为接近

参考文献

  1. ^ Scientists uncover history of ancient viruses as far back as 30 million years ago. phys.org. [2023-01-06]. (原始内容存档于2023-01-18) (英语). 
  2. ^ Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids. [2023-01-06]. (原始内容存档于2023-01-06). 
  3. ^ Page, Geology; Page, Geology. Scientists uncover history of ancient viruses as far back as 30 million years ago. Geology Page. 2016-03-08 [2023-01-06]. (原始内容存档于2023-01-06). 
  4. ^ Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals页面存档备份,存于互联网档案馆), by William E Diehl, Nirali Patel, Kate Halm, Welkin E Johnson. Boston College, United States. Areas: evolutionary biology, microbiology, infectious disease. Research Article Mar 8, 2016
  5. ^ Characterization of the low-copy HERV-Fc family: evidence for recent integrations in primates of elements with coding envelope genes页面存档备份,存于互联网档案馆), by Laurence Bénit, Alexandra Calteau, Thierry Heidmann. Virology, volume 312, issue 1, 20 July 2003, pages 159-168

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