NK-92细胞是一种人类自然杀伤细胞(NK细胞)的细胞系,分离自一位50岁的男性非霍奇金氏淋巴瘤病人[1]。NK-92能分泌肿瘤坏死因子(TNF-α)和γ-干扰素(IFN-γ)等细胞因子,还能通过穿孔素颗粒酶来攻击被细菌感染的细胞[2]

參考資料

  1. ^ ong, J., Maki, G., and Klingemann, H-G. (1994). “Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells”. Leukemia; 8: 652-58.
  2. ^ Paul S, Lal G. The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy. Frontiers in Immunology. 2017, 8: 1124. PMC 5601256 . PMID 28955340. doi:10.3389/fimmu.2017.01124 . 

外部連結