3-甲基苯甲醚
化合物
3-甲基苯甲醚是一种有机化合物，化学式为C8H10O。它可由3-甲基苯酚和碳酸二甲酯在十羰基二锰催化反应制得。[4]它和NBS在乙腈中于室温反应，可以得到4-溴-3-甲基苯甲醚；而在四氯化碳中光照回流，得到的主产物为3-甲氧基溴化苄。[5]碘-氧化汞在二氯甲烷中[6]，或NIS-TFA在乙腈中对其碘化，可以得到4-碘-3-甲基苯甲醚。[1]
| 3-甲基苯甲醚 | |
|---|---|
| |
| 别名 | 间甲基苯甲醚 3-甲氧基甲苯 |
| 识别 | |
| CAS号 | 100-84-5 
|
| PubChem | 7530 |
| ChemSpider | 21106135 |
| SMILES |
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| InChI |
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| InChIKey | OSIGJGFTADMDOB-UHFFFAOYSA-N |
| 性质 | |
| 化学式 | C8H10O |
| 摩尔质量 | 122.16 g·mol−1 |
| 外观 | 无色晶体[1] |
| 密度 | 0.9716 g/mL[2] |
| 熔点 | −47 °C（226 K）[3] −55.92 °C（217.23 K）[2] |
| 沸点 | 175.5 °C（448.6 K）[3] 176.5 °C（449.6 K）[2] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献
- ^ 1.0 1.1 Two Stereoinduction Events in One C−H Activation Step: A Route towards Terphenyl Ligands with Two Atropisomeric Axes. Angew. Chem. Int. Ed. 2018. doi:10.1002/anie.201801130. Supp Info. pp 19.
- ^ 2.0 2.1 2.2 Journal of the American Chemical Society. Volume 69, Issue 10. doi:10.1021/ja01202a060.
- ^ 3.0 3.1 "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2023-11-16].
- ^ Khusnutdinov, R. I., Shchadneva, N. A., & Mayakova, Y. Y. (2015). Methylation of phenol and its derivatives with dimethyl carbonate in the presence of Mn2(CO)10, W(CO)6, and Co2(CO)8. Russian Journal of Organic Chemistry, 51(3), 330–334. doi:10.1134/s1070428015030070
- ^ M. Carmen Carreno, Jose L. Garcia Ruano, Gema Sanz, Miguel A. Toledo, and Antonio Urbano. J. Org. Chem. 1995, 60, 16, 5328–5331 doi:10.1021/jo00121a064
- ^ Orito, K., Hatakeyama, T., Takeo, M., & Suginome, H. (1995). Iodination of Alkyl Aryl Ethers by Mercury(II) Oxide-Iodine Reagent in Dichloromethane. Synthesis, 1995(10), 1273–1277. doi:10.1055/s-1995-4089