3-甲基苯甲醚
化合物
3-甲基苯甲醚是一種有機化合物，化學式為C8H10O。它可由3-甲基苯酚和碳酸二甲酯在十羰基二錳催化反應製得。[4]它和NBS在乙腈中於室溫反應，可以得到4-溴-3-甲基苯甲醚；而在四氯化碳中光照回流，得到的主產物為3-甲氧基溴化苄。[5]碘-氧化汞在二氯甲烷中[6]，或NIS-TFA在乙腈中對其碘化，可以得到4-碘-3-甲基苯甲醚。[1]
| 3-甲基苯甲醚 | |
|---|---|
| |
| 別名 | 間甲基苯甲醚 3-甲氧基甲苯 |
| 識別 | |
| CAS號 | 100-84-5 
|
| PubChem | 7530 |
| ChemSpider | 21106135 |
| SMILES |
|
| InChI |
|
| InChIKey | OSIGJGFTADMDOB-UHFFFAOYSA-N |
| 性質 | |
| 化學式 | C8H10O |
| 摩爾質量 | 122.16 g·mol−1 |
| 外觀 | 無色晶體[1] |
| 密度 | 0.9716 g/mL[2] |
| 熔點 | −47 °C（226 K）[3] −55.92 °C（217.23 K）[2] |
| 沸點 | 175.5 °C（448.6 K）[3] 176.5 °C（449.6 K）[2] |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
參考文獻
- ^ 1.0 1.1 Two Stereoinduction Events in One C−H Activation Step: A Route towards Terphenyl Ligands with Two Atropisomeric Axes. Angew. Chem. Int. Ed. 2018. doi:10.1002/anie.201801130. Supp Info. pp 19.
- ^ 2.0 2.1 2.2 Journal of the American Chemical Society. Volume 69, Issue 10. doi:10.1021/ja01202a060.
- ^ 3.0 3.1 "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2023-11-16].
- ^ Khusnutdinov, R. I., Shchadneva, N. A., & Mayakova, Y. Y. (2015). Methylation of phenol and its derivatives with dimethyl carbonate in the presence of Mn2(CO)10, W(CO)6, and Co2(CO)8. Russian Journal of Organic Chemistry, 51(3), 330–334. doi:10.1134/s1070428015030070
- ^ M. Carmen Carreno, Jose L. Garcia Ruano, Gema Sanz, Miguel A. Toledo, and Antonio Urbano. J. Org. Chem. 1995, 60, 16, 5328–5331 doi:10.1021/jo00121a064
- ^ Orito, K., Hatakeyama, T., Takeo, M., & Suginome, H. (1995). Iodination of Alkyl Aryl Ethers by Mercury(II) Oxide-Iodine Reagent in Dichloromethane. Synthesis, 1995(10), 1273–1277. doi:10.1055/s-1995-4089