α-辅肌动蛋白3

Α-辅肌动蛋白3
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	1TJT、1WKU、3LUE
识别号
别名	ACTN3；, actinin alpha 3 (gene/pseudogene), ACTN3D, actinin alpha 3
外部ID	OMIM：102574 MGI：99678 GeneCards：ACTN3
基因位置（人类）
染色体	11号染色体
终止	66,563,334 bp
基因位置（小鼠）
染色体	小鼠19号染色体
终止	4,927,937 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• calcium ion binding; • protein homodimerization activity; • transmembrane transporter binding; • 金属离子结合; • integrin binding; • 血浆蛋白结合; • actin binding; • structural constituent of muscle;
细胞组分	• 细胞质基质; • 伪足; • 粘着斑; • 胞内; • 微丝; • 外排体;
生物学过程	• regulation of apoptotic process; • regulation of aerobic respiration; • negative regulation of glycolytic process; • negative regulation of calcineurin-NFAT signaling cascade; • transition between fast and slow fiber; • positive regulation of glucose catabolic process to lactate via pyruvate; • focal adhesion assembly; • muscle filament sliding; • skeletal muscle atrophy; • response to denervation involved in regulation of muscle adaptation; • negative regulation of oxidative phosphorylation; • positive regulation of skeletal muscle tissue growth; • regulation of the force of skeletal muscle contraction; • negative regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
直系同源
	89
	11474
	ENSG00000248746
	ENSMUSG00000006457
	Q08043
	O88990
	NM_001104; NM_001258371
	NM_013456
	NP_001095; NP_001245300
	NP_038484
	维基数据
查看/编辑人类	查看/编辑小鼠