促肾上腺皮质素释放素

促皮质素释放激素
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	3EHU、3EHT、1GOE
识别号
别名	CRH；, CRF, CRH1, corticotropin releasing hormone
外部ID	OMIM：122560 MGI：88496 HomoloGene：599 GeneCards：CRH
基因位置（人类）
染色体	8号染色体
终止	66,178,464 bp
基因位置（小鼠）
染色体	小鼠3号染色体
终止	19,749,560 bp
RNA表达模式
	; ;
	查阅更多表达数据
基因本体
分子功能	• hormone activity; • corticotropin-releasing hormone receptor 1 binding; • corticotropin-releasing hormone receptor 2 binding; • 血浆蛋白结合; • neuropeptide hormone activity; • signaling receptor binding; • corticotropin-releasing hormone activity;
细胞组分	• 细胞质; • 细胞本体; • varicosity; • 细胞外区域; • soma; • 细胞外空间;
生物学过程	• response to cocaine; • response to immobilization stress; • positive regulation of cortisol secretion; • steroid metabolic process; • positive regulation of protein phosphorylation; • negative regulation of luteinizing hormone secretion; • positive regulation of cell death; • 联想型学习; • ion homeostasis; • lung development; • diterpenoid metabolic process; • response to corticosterone; • female pregnancy; • negative regulation of norepinephrine secretion; • adrenal gland development; • synaptic transmission, dopaminergic; • negative regulation of cell death; • negative regulation of gene expression; • cellular response to dexamethasone stimulus; • positive regulation of corticosterone secretion; • response to estrogen; • locomotory exploration behavior; • regulation of NMDA receptor activity; • regulation of serotonin secretion; • positive regulation of calcium ion import; • glucocorticoid biosynthetic process; • positive regulation of gene expression; • positive regulation of digestive system process; • 出生; • response to pain; • positive regulation of circadian sleep/wake cycle, wakefulness; • positive regulation of cell population proliferation; • 下丘脑的发生; • 学习和记忆; • hormone-mediated apoptotic signaling pathway; • positive regulation of insulin secretion involved in cellular response to glucose stimulus; • response to ethanol; • inflammatory response; • negative regulation of circadian sleep/wake cycle, REM sleep; • response to ether; • positive regulation of behavioral fear response; • 讯息传递; • cellular response to cocaine; • 长时程增强作用; • 化学性突触传递; • negative regulation of epinephrine secretion; • negative regulation of glucagon secretion; • G protein-coupled receptor signaling pathway; • negative regulation of systemic arterial blood pressure; • positive regulation of cAMP-mediated signaling; • positive regulation of corticotropin secretion;
	Sources:Amigo / QuickGO
直系同源
	1392
	12918
	ENSG00000147571
	ENSMUSG00000049796
	P06850
	Q8CIT0
	NM_000756
	NM_205769
	NP_000747
	NP_991338
	维基数据
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