雄烯三醇

雄烯三醇(英語:Androstenetriol,縮寫AET,或稱為雄甾-5-烯-3β,7β,17β-三醇,androst-5-ene-3β,7β,17β-triol,βAET),分子式C19H30O3,是一種雄烷衍生物,是脫氫表雄酮(DHEA)在腎上腺代謝產物[1],性質上與DHEA、雄烯二醇類似[2]

雄烯三醇
識別資訊
  • (3S,7R,8R,9S,10R,13S,14S,17S)-10,13-Dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7,17-triol
CAS號2697-85-0
PubChem CID
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C19H30O3
摩爾質量306.45 g·mol−1
3D模型(JSmol英語JSmol
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O
  • InChI=1S/C19H30O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h10,12-17,20-22H,3-9H2,1-2H3/t12-,13-,14-,15-,16-,17-,18-,19-/m0/s1
  • Key:OEVZKEVBDIDVOI-YSZCXEEOSA-N

參考文獻

  1. ^ Ahlem, Clarence N.; Auci, Dominick L.; Nicoletti, Ferdinando; Pieters, Raymond; Kennedy, Michael R.; Page, Theodore M.; Reading, Christopher L.; Enioutina, Elena Y.; Frincke, James M. Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome. The Journal of Steroid Biochemistry and Molecular Biology. 2011, 126 (3): 87–94 [2024-02-01]. ISSN 0960-0760. PMID 21570467. S2CID 5123272. doi:10.1016/j.jsbmb.2011.04.010. (原始內容存檔於2023-12-14). 
  2. ^ Dillon, Joseph S. Dehydroepiandrosterone, Dehydroepiandrosterone Sulfate and Related Steroids: Their Role in Inflammatory, Allergic and Immunological Disorders. Current Drug Targets - Inflammation & Allergy. 2005, 4 (3): 377–385. PMID 16101547. doi:10.2174/1568010054022079. 

外部連結