2-吡啶甲酸苄酯

2-吡啶甲酸苄酯是一種有機化合物,化學式為C13H11NO2。它可由2-吡啶甲酰氯苯甲醇三乙胺存在下反應製得。[3]它和4-氯溴苄反應,可以得到4-氯苄基吡啶鎓-2-甲酸苄酯溴化物。[2]

2-吡啶甲酸苄酯
別名 吡啶-2-甲酸苯甲酯
識別
CAS號 71653-37-7  checkY
SMILES
 
  • O=C(OCC=1C=CC=CC1)C2=NC=CC=C2
性質
化學式 C13H11NO2
摩爾質量 213.23 g·mol−1
外觀 無色油狀物[1][2]
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

  1. ^ Raghunath Reddy Anugu, Sailu Munnuri, and John R. Falck. Picolinate-Directed Arene meta-C–H Amination via FeCl3 Catalysis. J. Am. Chem. Soc. 2020, 142, 11, 5266–5271. doi:10.1021/jacs.9b13753.
  2. ^ 2.0 2.1 Zhi Yang, Hanlin Chen, Linxi Wan, Xinyi Feng, Lingshuang Ma, Pei Tang, Fen-Er Chen. Sustainable synthesis of long-acting local anesthetics ropivacaine and levobupivacaine under batch and continuous flow via asymmetric hydrogenation. Org. Chem. Front. 2024. 11. 2891-2896. doi:10.1039/D4QO00072B.
  3. ^ Ju Yuel Baek, Yong-Joo Shin, Heung Bae Jeon, Kwan Soo Kim. Picolinyl group as an efficient alcohol protecting group: cleavage with Zn(OAc)2·2H2O under a neutral condition. Tetrahedron Letters. 2005. 46 (31): 5143-5147. doi:10.1016/j.tetlet.2005.05.125.