依法西泮
化合物
依法西泮（英語：Elfazepam[1]）是一種藥物，是苯二氮䓬類衍生物。[2]據推測，它與其他苯二氮䓬類藥物一樣具有鎮靜和抗焦慮作用。
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| CAS號 | 52042-01-0  |
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| 化學資訊 | |
| 化學式 | C19H18ClFN2O3S |
| 摩爾質量 | 408.87 |
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該藥物在動物體內具有食慾特性。[3][4]該藥物增加進食量的機制尚不清楚，並且一直在進行研究中。[5]已發現依法西泮能夠抑制胃酸的分泌。[6]
合成
參考資料
- ^ 美國專利第4,010,154號
- ^ Psychotropics.dk
- ^ Baile CA, McLaughlin CL. A review of the behavioral and physiological responses to elfazepam, a chemical feed intake stimulant. Journal of Animal Science. November 1979, 49 (5): 1371–95. PMID 396294. doi:10.2527/jas1979.4951371x.
- ^ Baile CA, Naylor J, McLaughlin CL, Catanzaro CA. Endotoxin-elicited fever and anorexia and elfazepam-stimulated feeding in sheep. Physiology & Behavior. August 1981, 27 (2): 271–7. PMID 7029576. S2CID 12408796. doi:10.1016/0031-9384(81)90269-9.
- ^ Keim DA, Baile CA, Bolton JR, Wangsness PJ, Della Fera MA. Abomasal function following injections of elfazepam and 9-aza-cannabinol. Pharmacology, Biochemistry, and Behavior. January 1979, 10 (1): 63–70. PMID 35793. S2CID 915512. doi:10.1016/0091-3057(79)90170-9.
- ^ Van Den Broek GW, Robertson J, Keim DA, Baile CA. Feeding and depression of abomasal secretion in sheep elicited by elfazepam and 9-aza-cannabinol. Pharmacology, Biochemistry, and Behavior. July 1979, 11 (1): 51–6. PMID 493298. S2CID 33152825. doi:10.1016/0091-3057(79)90296-x.