利米特羅

化合物

利米特羅INN:rimiterol)是第三代[1]短效β2腎上腺素受體激動劑[2][3]該藥物可通過靜脈注射氣霧給藥[4]利米特羅可用於治療與支氣管哮喘相關的支氣管痙攣[5][6][7]

利米特羅
臨床資料
懷孕分級
  • : A
ATC碼
法律規範狀態
法律規範
識別資訊
  • 4-{(S)-hydroxy[(2R)-piperidin-2-yl]methyl}benzene-1,2-diol
CAS號32953-89-2  ☒N
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.046.627 編輯維基數據鏈接
化學資訊
化學式C12H17NO3
摩爾質量223.27 g·mol−1
3D模型(JSmol英語JSmol
  • O[C@@H](c1ccc(O)c(O)c1)[C@@H]2NCCCC2
  • InChI=1S/C12H17NO3/c14-10-5-4-8(7-11(10)15)12(16)9-3-1-2-6-13-9/h4-5,7,9,12-16H,1-3,6H2/t9-,12+/m1/s1 checkY
  • Key:IYMMESGOJVNCKV-SKDRFNHKSA-N checkY

參見

參考資料

  1. ^ Palma-Carlos AG, Palma-Carlos GS. Beta-2-agonists of third generation. Allergie et Immunologie. April 1986, 18 (4): 31–2, 35. PMID 2899434. 
  2. ^ Lai CK, Twentyman OP, Holgate ST. The effect of an increase in inhaled allergen dose after rimiterol hydrobromide on the occurrence and magnitude of the late asthmatic response and the associated change in nonspecific bronchial responsiveness. The American Review of Respiratory Disease. October 1989, 140 (4): 917–23. PMID 2572192. doi:10.1164/ajrccm/140.4.917. 
  3. ^ Ydreborg SO, Svedmyr N, Thiringer G. Comparison of rimiterol and terbutaline, given by aerosol, in a long-term study. Scandinavian Journal of Respiratory Diseases. April 1977, 58 (2): 117–24. PMID 16339. 
  4. ^ Tarala, R. A.; Martyn, V.; Paterson, J. W. Effect of intravenous injection of rimiterol in asthma. British Journal of Clinical Pharmacology. 1981-09, 12 (3) [2024-03-24]. ISSN 0306-5251. PMC 1401816 . PMID 6117302. doi:10.1111/j.1365-2125.1981.tb01222.x. (原始內容存檔於2024-03-24). 
  5. ^ Linehan, W. D. A new bronchodilator, rimiterol hydrobromide (R 798): an open study of the bronchodilator, cardiovascular and arterial oxygen changes in asthmatic patients. Irish Journal of Medical Science. 1975-04, 144 (4) [2024-03-24]. ISSN 0021-1265. PMID 238916. (原始內容存檔於2024-03-24). 
  6. ^ Muittari, A. A comparison of rimiterol and salbutamol by inhalation at high and low dose in asthmatic patients. Respiration; International Review of Thoracic Diseases. 1978, 35 (3) [2024-03-24]. ISSN 0025-7931. PMID 25466. doi:10.1159/000193873. (原始內容存檔於2024-03-24). 
  7. ^ Pinder, R. M.; Brogden, R. N.; Speight, T. M.; Avery, G. S. Rimiterol: a review of its pharmacological properties and therapeutic efficacy in asthma. Drugs. 1977-08, 14 (2) [2024-03-24]. ISSN 0012-6667. PMID 19226. doi:10.2165/00003495-197714020-00001. (原始內容存檔於2024-03-24).