托維妥單抗
化合物
托維妥單抗(INN:Tovetumab)是一種抗PDGFRA單株抗體,設計用於治療癌症。[1]它由MedImmune開發,並試驗用於膠質母細胞瘤和非小細胞肺癌。[2]對於該藥物的開發於2013年停止。[3][4]
單株抗體 | |
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種類 | ? |
目標 | PDGFRA |
臨床資料 | |
ATC碼 |
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識別資訊 | |
CAS號 | 1243266-04-7 |
ChemSpider |
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UNII | |
KEGG | |
化學資訊 | |
化學式 | C6400H9906N1726O2002S54 |
摩爾質量 | 144,792.97 g·mol−1 |
存卡里
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Tovetumab, American Medical Association.
- ^ Liang M, Wang B, Schneider A, Vainshtein I, Roskos L. A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy. The AAPS Journal. November 2020, 23 (1): 4. PMID 33210183. S2CID 227067803. doi:10.1208/s12248-020-00523-3 .
- ^ Tovetumab. AdisInsight. Springer Nature Switzerland AG. [2024-03-01]. (原始內容存檔於2017-11-03).
- ^ Williams R. Discontinued in 2013: oncology drugs. Expert Opinion on Investigational Drugs. January 2015, 24 (1): 95–110. PMID 25315907. S2CID 23390614. doi:10.1517/13543784.2015.971154.