阿片樣肽受體
阿片樣肽受體或阿片類受體、阿片受體(英語:Opioid receptors)是一類以阿片樣肽為配體的G蛋白偶聯受體[1][2][3]。內源性類阿片物質包括強啡肽、腦啡肽、內啡肽、endomorphin和nociceptin。 阿片樣肽受體與生長抑素受體(SSTRs)有約40%的相似性。阿片受體廣泛分佈於大腦,且在脊髓與消化道中也有發現。
參考文獻
- ^ Dhawan BN, Cesselin F, Raghubir R, Reisine T, Bradley PB, Portoghese PS, Hamon M. International Union of Pharmacology. XII. Classification of opioid receptors. Pharmacol. Rev. December 1996, 48 (4): 567–92. PMID 8981566.
- ^ Janecka A, Fichna J, Janecki T. Opioid receptors and their ligands. Curr Top Med Chem. 2004, 4 (1): 1–17. PMID 14754373.
- ^ Waldhoer M, Bartlett SE, Whistler JL. Opioid receptors. Annu. Rev. Biochem. 2004, 73: 953–90. PMID 15189164. doi:10.1146/annurev.biochem.73.011303.073940.
外部連結
- 醫學主題詞表(MeSH):Opioid+Receptors
- Opioid Receptors. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. (原始內容存檔於2021-01-18).
- Corbett A, McKnight S, Henderson G. Opioid Receptors. BLTC Research. [2008-03-21]. (原始內容存檔於2021-03-14).
- Lomize A, Lomize M, Pogozheva I. Orientations of Proteins in Membranes (OPM) database. University of Michigan. [2008-03-21]. (原始內容存檔於2014-01-03).
- Mu-opioid receptor model (inactive state) with antagonist. [2008-03-21]. (原始內容存檔於2021-01-28).
- Mu-opioid receptor model in active state with agonist. [2008-03-21]. (原始內容存檔於2021-01-28).
- Guzman, F. Video lectures on opioid receptors. Pharmacology Corner. [2012-07-30]. (原始內容存檔於2013-12-29).