散乱蛋白
散乱蛋白（英语：Dishevelled，Dsh）是涉及钙离子与非钙离子Wnt信号通路的蛋白质家族。Dsh是一种胞浆内的磷酸化蛋白，作为卷曲受体的下游信号分子[1]。其得名于在果蝇中最初发现该基因时，其基因突变会导致身体和翅膀的刚毛定位错误[2]。
| Dishevelled specific domain | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 鉴定 | |||||||||||
| 标志 | Dishevelled | ||||||||||
| Pfam | PF02377（旧版） | ||||||||||
| InterPro | IPR003351 | ||||||||||
| PROSITE | PDOC50841 | ||||||||||
| |||||||||||
参考文献
- ^ Penton A, Wodarz A, Nusse R. A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin. Genetics. June 2002, 161 (2): 747–62. PMC 1462152
. PMID 12072470.
- ^ Wallingford JB, Habas R. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development. October 2005, 132 (20): 4421–36. PMID 16192308. doi:10.1242/dev.02068.
