苯茚二酮

化合物

苯茚二酮(英语:Phenindione,化学名:2-苯基-1,3-茚满二酮),是一种有机化合物,分子式C15H10O2,属于1,3-茚满二酮衍生物,可作为抗凝剂,功能与鼠药华法林类似[1][2]

苯茚二酮
临床资料
AHFS/Drugs.com国际药品名称
怀孕分级
给药途径Oral
ATC码
药物动力学数据
血浆蛋白结合率88%
生物半衰期5 to 10 hours
识别信息
  • 2-phenyl-1H-indene-1,3(2H)-dione
CAS号83-12-5  checkY
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.001.323 编辑维基数据链接
化学信息
化学式C15H10O2
摩尔质量222.24 g·mol−1
3D模型(JSmol英语JSmol
  • O=C2c1ccccc1C(=O)C2c3ccccc3
  • InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H checkY
  • Key:NFBAXHOPROOJAW-UHFFFAOYSA-N checkY

参考文献

  1. ^ Naisbitt DJ, Farrell J, Chamberlain PJ, Hopkins JE, Berry NG, Pirmohamed M, Park BK. Characterization of the T-cell response in a patient with phenindione hypersensitivity. The Journal of Pharmacology and Experimental Therapeutics. June 2005, 313 (3): 1058–65. PMID 15743920. S2CID 17052792. doi:10.1124/jpet.105.083758. 
  2. ^ Sweetman SC (编). Martindale: The Complete Drug Reference 36th. London: Pharmaceutical Press. 2009. "Phenindione", p. 1369. 

外部链接