RTI-171

化合物

RTI-171是一种有机化合物,化学式C19H24N2O,化学名:(–)-2β-(3-甲基异恶唑-5-基)-3β-(对甲苯基)莨菪烷(英语:(–)-2β-(3-Methylisoxazol-5-yl)-3β-(p-tolyl)tropane),开发代号:RTI-4229-171,可作为多巴胺再摄取抑制剂,已用于动物实验[1]

RTI-171
识别信息
  • 3-methyl-5-[(1S,3S,4S,5R)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-4-yl]-1,2-oxazole
CAS号178929-75-4  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H24N2O
摩尔质量296.41 g·mol−1
3D模型(JSmol英语JSmol
  • n1oc(cc1C)[C@@H]3[C@@H]4N(C)[C@H](C[C@@H]3c2ccc(cc2)C)CC4
  • InChI=1S/C19H24N2O/c1-12-4-6-14(7-5-12)16-11-15-8-9-17(21(15)3)19(16)18-10-13(2)20-22-18/h4-7,10,15-17,19H,8-9,11H2,1-3H3/t15-,16+,17+,19-/m0/s1 ☒N
  • Key:JWOFBAPJYPWTNI-FAJBIJEISA-N ☒N

参考文献

  1. ^ Kimmel HL, Carroll FI, Kuhar MJ. Locomotor stimulant effects of novel phenyltropanes in the mouse. Drug and Alcohol Dependence. December 2001, 65 (1): 25–36. PMID 11714587. doi:10.1016/S0376-8716(01)00144-2.