甲醯乙酸
化合物
甲醯乙酸是一種有機化合物,化學式為C3H4O3。它可由蘋果酸、高碘酸和N-溴代煙醯胺在乙酸汞催化下反應製得[1],或由α-當歸內酯經高碘酸鈉/四氧化鋨氧化得到。[2]
甲醯乙酸 | |
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別名 | 3-氧代丙酸 縮蘋果酸半醛 |
識別 | |
CAS號 | 926-61-4 ![]() |
SMILES |
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性質 | |
化學式 | C3H4O3 |
摩爾質量 | 88.06 g·mol−1 |
相關物質 | |
相關化學品 | 乙醯乙酸 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
在一種銥的配合物的催化下,它可以和甲酸銨反應,生成甘氨酸[3]。琥珀酸半醛脫氫酶(YNEI)可以使甲醯乙酸轉化為丙二酸。[4]
參考文獻
- ^ Pushpalatha, L. Kinetics and mechanism of oxidation of malic acid by N-bromonicotinamide. International Journal of Chemistry (Mumbai, India), 2012. 1 (2): 199-204. ISSN 2249-2119.
- ^ Traverso, G.; Pirillo, D.; Strazzolini, P. On the coupled sodium periodate/osmium tetroxide oxidation of some unsaturated γ-lactones. Farmaco, Edizione Scientifica, 1979. 34 (12): 1071-1072. ISSN 0430-0920.
- ^ Nguyen, Dat P.; Sladek, Rudolph N.; Do, Loi H. Scope and limitations of reductive amination catalyzed by half-sandwich iridium complexes under mild reaction conditions. Tetrahedron Letters. 2020-08, 61 (32): 152196. doi:10.1016/j.tetlet.2020.152196.
- ^ Song, Chan Woo; Kim, Je Woong; Cho, In Jin; Lee, Sang Yup. Metabolic Engineering of Escherichia coli for the Production of 3-Hydroxypropionic Acid and Malonic Acid through β-Alanine Route. ACS Synthetic Biology (American Chemical Society (ACS)). 2016-03-14, 5 (11): 1256–1263. ISSN 2161-5063. doi:10.1021/acssynbio.6b00007.