Template:PBB/7852

Chemokine (C-X-C motif) receptor 4
CXCR4 in complex with IT1t(PDB 3OE9)
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 2K03, 2K04, 2K05, 3ODU, 3OE0, 3OE6, 3OE8, 3OE9
标识
代号	CXCR4; CD184; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM
扩展标识	遗传学：162643 鼠基因：109563 同源基因：20739 IUPHAR:  CXCR4 ChEMBL: 2107 GeneCards: CXCR4 Gene
基因本体论描述 分子功能 · actin binding · G-protein coupled receptor activity · protein binding · coreceptor activity · C-X-C chemokine receptor activity · C-X-C chemokine binding · ubiquitin protein ligase binding · myosin light chain binding · ubiquitin binding 细胞成分 · cytoplasm · plasma membrane · external side of plasma membrane · cell surface · integral to membrane · cytoplasmic membrane-bounded vesicle · growth cone · cell leading edge · cytoplasmic vesicle 生物过程 · activation of MAPK activity · patterning of blood vessels · response to hypoxia · ameboidal cell migration · neuron migration · dendritic cell chemotaxis · apoptotic process · inflammatory response · G-protein coupled receptor signaling pathway · elevation of cytosolic calcium ion concentration · germ cell development · brain development · motor neuron axon guidance · germ cell migration · response to virus · viral reproduction · virus-host interaction · calcium-mediated signaling · viral reproductive process · entry into host cell · regulation of cell migration · T cell proliferation · neutrophil activation · myelin maintenance · positive regulation of oligodendrocyte differentiation · regulation of chemotaxis · neural precursor cell proliferation Sources: Amigo / QuickGO
RNA表达模式
更多表达数据
直系同源体
物种	人类	小鼠
Entrez	7852	12767
Ensembl	ENSG00000121966	ENSMUSG00000045382
UniProt	P61073	P70658
mRNA序列	NM_001008540	NM_009911
蛋白序列	NP_001008540	NP_034041
基因位置	Chr 2: 136.87 – 136.88 Mb	Chr 1: 128.59 – 128.59 Mb
PubMed查询	[1]	[2]