甘油-3-磷酸脱氢酶 [NAD(P)+]

甘油-3-磷酸脫氫酶 [NAD(P)⁺]（英語：glycerol-3-phosphate dehydrogenase [NAD(P)⁺]，EC 1.1.1.94 （頁面存檔備份，存於網際網路檔案館）），是一種以NAD⁺或NADP⁺為受體、作用於供體CH-OH基團上的氧化還原酶。這種酶能催化以下酶促反應：

甘油-3-磷酸脫氫酶 [NAD(P)+]
命名 系統命名 sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase 縮寫 別名 L-glycerol-3-phosphate:NAD(P) oxidoreductase; glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)); glycerol 3-phosphate dehydrogenase (NADP); glycerol-3-phosphate dehydrogenase [NAD(P)]
識別碼
EC編號	1.1.1.94
CAS號	37250-30-9
資料庫
IntEnz	IntEnz瀏覽
BRENDA	BRENDA入口
ExPASy	NiceZyme瀏覽
KEGG	KEGG入口
MetaCyc	代謝路徑
PRIAM	概述
PDB	RCSB PDB PDBj PDBe PDBsum
基因本體	AmiGO / EGO
搜索 PMC 相關文獻 PubMed 相關文獻

sn-甘油-3-磷酸 + NAD(P)⁺ $\rightleftharpoons$ 磷酸甘油酮 + NAD(P)H + H⁺

甘油-3-磷酸脫氫酶 [NAD(P)⁺]主要參與磷酸甘油酯的代謝過程。大腸桿菌（Escherichia coli）的甘油-3-磷酸脫氫酶 [NAD(P)⁺]顯示出對NADPH的B域的特異性。

參考文獻

• Kito M, Pizer LI. Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from Escherichia coli. J. Biol. Chem. 1969, 244 (12): 3316–3323. PMID 4389388. 
• Edgar JR, Bell RM. Biosynthesis in Escherichia coli fo sn-glycerol 3-phosphate, a precursor of phospholipid. J. Biol. Chem. 1978, 253 (18): 6348–6353. PMID 355254. 
• Edgar JR, Bell RM. Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid. Kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J. Biol. Chem. 1978, 253 (18): 6354–6363. PMID 28326. 
• Edgar JR, Bell RM. Biosynthesis in Escherichia coli of sn-glycerol-3-phosphate, a precursor of phospholipid. Further kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J. Biol. Chem. 1980, 255 (8): 3492–3497. PMID 6767719.